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Type:
Educational Exhibit
Keywords:
Abdomen, MR, CT, Diagnostic procedure, Education and training, Genetic defects
Authors:
F. Rego Costa, C. Esteves, L. Melão; Porto/PT
DOI:
10.1594/ecr2015/C-0339
Conclusion
Radiology plays a central role in the management of VHL disease.
Imaging detection of the various abdominal lesions requires implementation of screening protocols for high-risk gene carriers.
Screening protocols for detection of the most common abdominal lesions commonly include the following:
- Annual physical examination and urine test;
- Annual abdominal US examination,
beginning at 11 years old;
- Abdominal CT scanning every 2/3 years,
beginning at 20 years old (more often if multiple renal cysts are present);
- Annual 24-hour urine collection for vanillylmandelic acid levels,
beginning at 2 years old.
These screening protocols are the key for early detection of treatable lesions,
improving the probability of a successful conservative treatment.