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Type:
Educational Exhibit
Keywords:
Cardiac, Cardiovascular system, Arteries / Aorta, CT, CT-Angiography, CT-Quantitative, Computer Applications-3D, Diagnostic procedure, Ischaemia / Infarction, Arteriosclerosis
Authors:
S. Seitun1, S. Boccalini1, I. Budaj1, M. Castiglione Morelli1, A. Galletto2, C. Zawaideh1, I. Rota1, F. Cademartiri3, C. Ferro1; 1Genoa/IT, 2Borgio Verezzi/IT, 3Monastier di Treviso/IT
DOI:
10.1594/ecr2015/C-0956
Background
Up to today CT is the most accurate examination for a non-invasive assessment of coronary atherosclerosis,
however,
based on anatomic-morphologic characteristics only,
it’s not possible to determine the physiopathological meaning of a coronary atherosclerotic plaque.
As shown in studies with invasive measurement of the coronary fractional flow reserve obtained during coronarography [1],
the downstream perfusion alteration of an intermediate coronary stenosis (40-70% of lumen restriction) can be uncertain.
For these reasons,
in clinical practice,
morphologic informations regarding the coronary arteries acquired with coronary-CT are often integrated with a functional imaging examination,
such as ECHO-stress,
SPECT,
PET or MRI.
The functional data are essential in the diagnostic-therapeutic management of the patient.
With the latest generation CT scans it’s possible to perform dynamic perfusion studies that combine in a single exam functional and anatomical data.
A CT acquisition obtained during an hyperemic pharmacological induced stress condition (Adenosine,
Dipyridamole) can offer an important contribution and help to interpret more exhaustively the results.