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Type:
Educational Exhibit
Keywords:
Seizure disorders, Lymphoma, Dementia, Contrast agent-intravenous, Computer Applications-Detection, diagnosis, Biopsy, MR, CT, Oncology, Neuroradiology brain, CNS
Authors:
V. Vivas Escalona, B. A. Givica Pérez; Las Palmas/ES
DOI:
10.1594/ecr2015/C-1087
Background
IVL is a rare subtype of Lymphoma.
It is usually due to multifocal proliferation of tumor cells (large B-cells) in small vessels.
It has a predilection for central nervous system (CNS) and skin,
but it can affect kidneys,
bone marrow,
breast,
uterus,
testicles,
lungs,
larynx and adrenal glands.
It has been reported association with Epstein Barr virus also.
Usually,
it affects patients in their 6th to 7th decades of life,
with a male-female ratio of 2:1.
The survival is about 7 to 13 months with a mortality rate of 80%.
In rare occasions may be regression of the symptoms but most of the diagnosis is made post-mortem.
Diagnosis is difficult because of its variability in clinical manifestations and nonspecific laboratory results with imaging findings also diverse,
which is why we would like to review and describe them.