1. LEARNING OBJECTIVES The purpose of our educational exhibit is to: Review sarcoidosis in terms of clinical manifestations, diagnosis, prognosis and treatment; Analyse and illustrate the radiologic manifestations of sarcoidosis in multiple anatomic locations, particularly in thorax, breast, upper abdomen, musculoskeletal system and central nervous system.

2. INTRODUCTION ΩSarcoidosis is a systemic disease of unknown cause, with a variety of clinical and radiologic manifestations and with variable prognosis. Commonly, it affects young and middle-aged patients, with a slightly higher prevalence in women. The most common radiologic finding is bilateral hilar lymphadenopathy. Right paratracheal, left aortic-pulmonary window and subcarinal lymph node involvement can also be seen, often withpulmonary infiltrates associatedFig. 1. Extrathoracic involvement is the first manifestation of diseasein 50%of symptomatic patients. Although skin and ocular lesions are common (and diagnosedon physical...

4. IMAGING FINDINGSOF SARCOIDOSIS 4.1. THORAX Thoracic involvement is reported in up to 90% of patients and oftenmanifests as asymptomatic mediastinal lymph node involvement. More than 40 years ago, it wasdeveloped a sarcoidosis staging system based on the pattern of chest radiographic findings, a system still widely used because of its great prognostic value.There are five radiologic stages of thoracic changes and50%of patients present with stage 1. Although hilar adenopathy is easily recognized on chest radiographs, computed tomography (CT) is superior for demonstrating subtle mediastinal...

5. CONCLUSION Sarcoidosis is a multisystem disorder. The knowledge oftypical and atypical radiologic manifestations of sarcoidosis in differentanatomic locations, thoracic and extrathoracic, plays a essential role in thediagnosis.

6. PERSONAL INFORMATION Elisa Ferreira de Melo Abreu Radiology Department ofInstituto Português de Oncologia de Lisboa, Francisco Gentil, EPE - Lisbon, Portugal e-mail: [email protected]

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