Comparison of T2 Weighted Images/ Diffusion Weighted Imaging andT2 Weighted Images/ Dynamic Contrast Enhanced MRI for assessing the depth of myometrial invasion in endometrial cancer

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Congress:

ECR 2016

Poster Number:

C-0323

Type:

Scientific Exhibit

Keywords:

Genital / Reproductive system female, Oncology, Contrast agents, MR, MR-Diffusion/Perfusion, MR-Functional imaging, Observer performance, Contrast agent-other, Cancer, Pathology

Authors:

M. A.-F. E. Mourad¹, E. Moussa²; ¹Minia/EG, ²Alexandria/EG

DOI:

10.1594/ecr2016/C-0323

DOI-Link:

https://dx.doi.org/10.1594/ecr2016/C-0323

Results

The examined sequences were investigated for the tumor presence, myometrial invasion localization for tumor depth and the depth of the myometrial invasion either superficial involving no or less than half of the myometrium or deep involving more than half of the myometrium.

The examined cases are divided into thirty-nine cases (63%) of superficial myometrial invasion and twenty-three (37%) cases of deep myometrial invasion according to histopathological examination. MRI confirmation revealed that combined T2/ DWI shows 35/39 patients of superficial myometrial invasion, 22/23 of deep myometrial invasion. Combined T2/ DCE shows 30/39 patients of superficial myometrial invasion, 19/23 patients of deep myometrial invasion (Table1).

Table 1. Comparison between the histologically confirmed superficial and deep myometrial invasion and MRI examination (DWI/T2WI & DCE/T2WI)

Myometrial invasion by

Histopathology(62)

DWI/T2WI

DCE/T2WI

Deep <50% (23)

22/23

19/23

Superficial >50% (39)

35/39

30/39

The diagnostic accuracy, sensitivity and specificity were evaluated as follow: the diagnostic accuracy, sensitivity, specificity of combined T2 / DWI were 92%,90% and 95.6% while for the combined T2/ DCE were 79%,77% and 82.6% for < 50% myomterial invasion (Table 2) & > 50% myometrial invasion (Table3).

Table 2. shows the diagnostic accuracy, sensitivity, specificity of combined T2 / DWI & combined T2/ DCE for <50% myometrial invasion

	Diagnostic accuracy	Sensitivity	Specificity
Combined T2 / DWI	92%	90%	95.6%
Combined T2/ DCE	79%	77%	82.6%

Table 3. shows the diagnostic accuracy, sensitivity, specificity of combined T2 / DWI & combined T2/ DCE for >50% myometrial invasion

	Diagnostic accuracy	Sensitivity	Specificity
Combined T2 / DWI	92%	95.6%	90%
Combined T2/ DCE	79%	82.6%	77%