Aims and objectives
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To evaluate optimal window settings for display of virtual monoenergetic reconstructions in third-generation dual-source,
dual-energy computed tomography (DECT) of the liver.
Methods and materials
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Twenty-nine subjects were prospectively evaluated with DECT in arterial (AP) and portal venous (PVP) phases.
Three reconstructed datasets were calculated: standard linearly-blended (LB120),
70-keV standard monoenergetic (M70),
and 50-keV advanced image-based virtual monoenergetic (M50+).
Two readers assessed optimal window (width and length,
W/L) settings,
establishing a mean for each reconstruction which was used for a blinded assessment of liver lesions.
Results
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The optimal W/L settings for M50+ were significantly higher for both AP (W=429.3±44.6HU,
L=129.4±9.7HU) and PVP (W=376.1±14.2HU,
L=146.6±7.0HU) than for LB120 (AP,
W=215.9±16.9HU,
L=82.3±9.4HU) (PVP,
W=173.4±8.9HU,
L=69.3±6.0HU) and M70 (AP,
W=247.1±22.2HU,
L=72.9±6.8HU) (PVP,
W=232.0±27.9HU,
L=91.6±14.4HU).
Use of the optimal window setting for M50+ vs.
LB120 resulted in higher sensitivity (AP,
100% vs.
86%; PVP,
96% vs.
63%).
Conclusion
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Application of dedicated window settings results in improved liver lesion detection rates in advanced image-based virtual monoenergetic DECT when customized for arterial and portal venous phases.
Personal information
Dr.
Damiano Caruso,
MD
- Sapienza University of Rome
- Medical University of South Carolina
[email protected]
References
Husarik DB,
Gordic S,
Desbiolles L,
et al.
Advanced Virtual Monoenergetic Computed Tomography of Hyperattenuating and Hypoattenuating Liver Lesions: Ex-Vivo and Patient Experience in Various Body Sizes.
Invest Radiol 2015;50(10):695-702.
Leng S,
Yu L,
Fletcher JG, McCollough CH.
Maximizing Iodine Contrast-to-Noise Ratios in Abdominal CT Imaging through Use of Energy Domain Noise Reduction and Virtual Monoenergetic Dual-Energy CT.
Radiology 2015;276(2):562-70.
Schabel C,
Bongers M,
Sedlmair M,
et al.
Assessment of the hepatic veins in poor contrast conditions using dual energy CT: evaluation of a novel...
