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Keywords:
Colon, Computer applications, Radioprotection / Radiation dose, CT, CAD, Image manipulation / Reconstruction, Colonography CT, Computer Applications-3D, Cancer
Authors:
G. De Paoli Barbato, M. Bassi, E. Raimondi, A. Spiller, R. Rizzati, M. tilli, M. Giganti, G. Benea; Ferrara/IT
DOI:
10.1594/ecr2017/B-0201
Methods and materials
Fifty patients (31 males,
19 females,
mean age 69,7 years) underwent CTC (Philips Healthcare 128x0.625mm,
rotation time 0.5s,
pitch 0.601),
with SD (120 kV,
50 mAs 4,6 ± 1,3 mSv) and ULD (120 kV,
10 mAs,
0,87± 0,13 mSv) both with two acquisitions per decubitus prone and supine.
CTC was perfomed after intestinal cleansing with specific diet and osmotic laxatives (Movicol® - Norgine,
Italy) during the previous three days,
fecal tagging with iodine MDC (Gastrografin® - Bayer,
Germany) the evening before and the morning of the exam; spasmolytic (Buscopan® - Boehringer Ingelheim,
Italy) was administered to patients without contraindications.
Images of SD and ULD were reconstructed with HIR and MBIR; CAD system was applied complementary to all reconstructions.
Two indipendent radiologists with high experience in reading CTC (over 500 exams),
reviewed obtained images separately randomized during a 5 months period to avoid recall-bias,
and recorded colonic findings (polyps/cancer),
extracolonic findings and CAD detections.
Polyps were classified by size (< 6 mm,
between 6-9 mm,
≥ 10 mm),
shape (flat,
sessile/peduncolated,
non-polypoid) and location (rectum,
sigmoid,
descending,
transverse,
ascending colon and cecum).
Only E4 extracolonic findings (classified with C-RADS) were recorded.
CAD results were reported,
comparing total and significant findings between SD and ULD-CTC.