This poster is published under an
open license. Please read the
disclaimer for further details.
Type:
Educational Exhibit
Keywords:
Diagnostic procedure, Biopsy, Ultrasound, MR, Oncology, Musculoskeletal soft tissue, Neoplasia
Authors:
A. Fischetti1, I. Mussetto2, N. Romano1, R. Bianchi2, G. Roselli3, A. Muda1; 1Genova/IT, 2GENOA/IT, 3Firenze (FI)/IT
DOI:
10.1594/ecr2017/C-0710
Background
Liposarcoma is the second most common of soft-tissue sarcomas,
accounting for 14%–18% of these lesions (1,
2,
3).
Liposarcoma originates from primitive mesenchimal cells and is classified into five histological subtypes: well differented,
myxoid,
de-diffrented,
pleomorphic and mixed.
The prognosis of patients depends on the histological subtype (1,
4).
Myxoid Liposarcoma is the second common type of Liposarcoma and occurs most commonly in the lower extremities,
particularly the thigh: they are most frequently intermuscular or subcutaneous lesions (1,
4,).
Other localizations are upper extremities and retroperitoneum.
It is usually found in adults between 18-67 years,
rarely in children,
and has an intermediate prognosis.
The clinical presentation is a painless,
palpable mass of soft-tissues: lesion may be quite large (> 15 cm) at presentation(4,
5,
6).
Histopathological features show a mixture of non-lipogenic cells and lipoblasts in a prominent myxoid stroma,
with a rich arborizing capillary vasculature [Fig.1].
The percentage of fat is variable,
often less than 10-25% of tumor volume (1,
7,
8,
9),
and this variability influence the MRI imaging findings.