Learning objectives
The aim of our study is to describe Magnetic Resonance Imaging (MRI) and Computed Tomography (CT) features in children diagnosed with rhabdomyosarcoma (RMS),
incorrelation to histologic type,
location,
extension,
recurrence and metastases.
Background
Rhabdomyosarcoma is a mesenchymal sarcoma derived from primary muscle cells (rhabdomyoblasts) and represents 3- 5%of malignant solid tumors in childhood.
Among the extracranial solid tumors of childhood,
RMS is the third most common neoplasm after neuroblastoma and Wilms’ tumor.
There is a slight male predominance,
with a peak incidence during the first 5 years of life.
Members of families with Li-Fraumeni syndrome,
children with Beckwith-Wiedemann syndrome,
neurofibromatosis and Costello syndrome have a high risk of developing rhabdomyosarcoma.
Children between the ages of 1 and 9...
Findings and procedure details
Our study included twenty children (eleven boys and nine girls,
age range 3y-13y)with histologically confirmed RMS.
The site of primary RMS was:
infratemporal fossa (n=6),
Fig. 2 ,
Fig. 3,
pelvis (n=5),
Fig. 4 ,
Fig. 5,
parapharyngeal space (n=2) Fig. 6 ,
pterygopalatine fossa (n=2),
Fig. 7,
orbital roof (n=1),
Fig. 8 ,
sphenoid sinus(n=1),
Fig. 9 ,
prostate(n=1),
Fig. 10 ,
Fig. 11 ,
Fig. 12 ,
testicle(n=1) Fig. 13 ,
kidney (n=1).
Our patients’ group RMS histologic subtypes were: embryonal (11 children)...
Conclusion
Rhabdomyosarcoma will be treated with surgery to remove the tumor if it is possible to do so without causing major damage or disfigurement.
Although the goal is to completely remove the tumor,
this is often not possible.
Whether the tumor appears to have been completely removed or not,
all children with rhabdomyosarcoma should receive chemotherapy.
If cancer is left behind after surgery or if the cancer has some less favorable traits and it hasn't spread to distant sites,
radiation therapy will also be given.
Your...
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