Aims and objectives
Also called osteoclastoma,
giant cell tumor (GCT) accounts for approximately 7% of primary osseous tumors and 20% of benign tumors.
It has been diagnosed in patients upto the age of 50,
although its incidence is greatest in the 3th decade of life(1).
Classically GCT is characterised radiologically as a lytic lesion centered in the epiphysiometaphyseal region of the distal femur,
proximal tibia,
proximal humerus and distal radius of an skeletally mature patient.
Most are eccentric and surrounded by a circumscribed non sclerotic border.
Despite this...
Methods and materials
We have reviewed the radiological procedures performed in our institution on 136 patients diagnosed with GCT from 1990 to 2016,
of whom we excluded 33 because of the lack of imaging studies prior to surgery or due to the poor quality of the studies,
which reduces the overall number of analyzed cases to 103.
Although the literature refers to a slight predominance of the female sex(2),
in our sample we found 53 men and 50 women,
aged between 12 and 79 years,
and an average...
Results
IMAGING TESTS
Like in any other bone tumor,
imaging is initiated with Conventional Radiology (Xray) in at least two views.
Computed Tomography (CT) with multiplanar reconstruction is indicated to delineate the bone cortex and the tumoral borders in respect to the surrounding marrow,
whereas Magnetic Resonance (MRI) stands out for its greater ability to characterize tissue and internal tumor structure,
and to differentiate the tumor from the peritumoral soft tissues.
Although Conventional Angiography was traditionally used to determine its relationship with vessels,
currently its use...
Conclusion
Beyond the classic description of bone giant cell tumor as a tumor that appears in patients with closed metaphysis,
characterized by a lithic nature,
epiphyseal,
subchondral and eccentric location,
and geographic delimitation with no sclerotic border,
there are unusual forms of presentation,
which must be known so as not to misdiagnose.
In addition,
there are other signs that characterize GCT,
such as their frequent internal trabeculations,
insufflating behaviour,
hypercellular and hypervascular nature,
and above all,
their frequent aggressive radiological presentation,
which are not necessarily related...
References
BIBLIOGRAPHY
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D.
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K.
(1986).
Bone tumors: General aspects and data on 8,547 cases.
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K.,
Moore,
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Walker,
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& Jaksha,
J.
(2003).
Multifocal,
metachronous,
giant cell tumor of the lower limb.
Skeletal radiology,
32(3),
147-150.
3> Helms,
C.
A.
(2013).
Fundamentals of skeletal radiology.
Elsevier Health Sciences.
4> Campanacci,
M.,
Baldini,
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Boriani,
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& Sudanese,
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(1987).
Giant-cell tumor of bone.
J Bone Joint Surg Am,
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5> Purohit,
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& Pardiwala,
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(2007).
Imaging...