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Keywords:
Image verification, Embolism / Thrombosis, Connective tissue disorders, Technology assessment, Image manipulation / Reconstruction, CT, Lung
Authors:
I. Leineman, R. Faizenberg, T. Golimbievskaya, M. Shostak, I. Itskovich, V. Mazurov; Saint-Petersburg/RU
DOI:
10.1594/ecr2017/C-1760
Results
According to the diagnostician's conclusions an addition of post-processing software to CT increased sensitivity of CT in diagnosis of pulmonary vasculitis and thrombosis in situ in patients with SLE and APS (Fig. 3).
No differences in assessment involved regions were detected during the comparison of the results of color maps with CT angiograms (p = 0.031) and perfusion scans (p=0.042).
Statistics showed that the mean area under the receiver operating characteristic curve value increased significantly (p<0.05) by using post-processing software in assessment of pulmonary vasculitis (Fig. 4) from 0.826 (95% CI 0.747-0.890) to 0.962 (95% CI 0.910-0.988) and thrombosis in situ (Fig. 5) from 0.752 (95% CI 0.665-0.827) to 0.919 (95 CI 0.855-0.961).
Variants that were associated with the results of color maps in a significant manner were:
- rate of diffusion capacity (p=0.006),
- hypocomplementemia (p=0.01),
- hypoxemia (p=0.003),
- pulmonary hypertension (p=0.01).
3 cases demonstrated the advantages of post-processing software in patients with SLE and APS:
- Differentiating between pulmonary vasculitis and pneumonia infiltration (Fig. 6).
- Detecting thrombosis and infarctions in patients with SLE and secondary APS (Fig. 7).
- To evaluate treatment-related changes (Fig. 8)