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Keywords:
Haematologic, MR, Staging, Haematologic diseases
Authors:
L. Bertuzzo, A. Bissoli, M. C. Ambrosetti, M. Tinelli, R. Pozzi-Mucelli; Verona/IT
DOI:
10.1594/ecr2017/C-2707
Results
Bone marrow infiltration
The presence of bone marrow infiltration was significantly superior in patients classified as MM and P (86,7%) than those classified as MGUS and SMM (12,5%) (p=0,0010) (Fig. 7). We found bone marrow infiltration in 14 out of 23 patients (60,8%): 1 with SMM,
11 with MM and 2 with P.
On the contrary,
we did not find any evidence of bone marrow infiltration in patients with MGUS (Fig. 8).
The degree of infiltration was positively correlated with the severity of the clinical stage (p=0,0085). We found a low grade infiltration in 1 patient with SMM and 2 with MM (13%).
None of the patients with MGUS and P had any evidence of low grade infiltration. A moderate infiltration was detected in 4 patients with MM and 2 with P (26%).
We did not find moderate infiltration in patients with MGUS and SMM. We found a severe infiltration in 5 patients with MM (21,7%).
None of the patients with MGUS,
SMM and P had any evidence of severe infiltration (Fig. 9).
Focal lesions
We found focal lesions in 16 patients (69,5%): 1 with SMM,
12 with MM and 3 with P.
None of the patients with MGUS had focal lesions (Fig. 8). The presence of focal lesions was definitely superior in patients with MM and P (100%) than those with MGUS and SMM (12,5%) (p<0,0001) (Fig. 10).
At the qualitative analysis of the lesions,
on T1-weighted images 50% of the lesions obtained a score of 1,
29% a score of 2 and 21% a score of 3.
On STIR images 42% obtained a score of 1,
32% a score of 2,
26% a score of 3. On DWI images only 3% of the lesions obtained a score of 1,
15% a score of 2,
82% a score of 3 (Fig. 11).
We found that conspicuity of focal lesions was higher with DWI than T1 and STIR sequences (p<0,0001).