Keywords:
Cancer, Efficacy studies, Ultrasound, Mammography, Breast
Authors:
G. G. N. Mello, A. P. C. Moura, V. L. N. Aguillar, L. F. Chala, M. Aracava; São paulo, são paulo/BR
DOI:
10.1594/ecr2018/C-0445
Results
15 additional cancers were detected: 7 by US-only,
7 by US and DBT and 1 by DBT-only.
BUS detected 14 of 15 additional tumors and DBT detected 8 of them.
(Table 3).
Cancer detection rate was 5.6 for DM alone,
6.8 for DM plus DBT,
7.7 for DM plus US and 7.9 for DM plus DBT combined to US.
So,
the incremental cancer detection rate was 1.2 cancers by DBT, 2.1 by US and 2.3 by DBT plus US,
per 1000 screening exams (Table 4)
All cancers detected by US-only were invasive,
node negative,
HR positive,
less than 1 cm and presented as hypoechoic masses or acoustic shadowing,
in women with breast density ACR C or D.
None of them was seen by tomosynthesis,
even retrospectively (Table 5 and Fig 1)
Cancers detected by DBT were 88% invasive (2 ILC + 5 IDC + 1 RS with DCIS),
only one with LN micrometastasis,
all HR positive,
measuring up to 1.7 cm,
presenting mainly as architectural distortion (Table 6 and Fig 2,
3)
Positive predictive value 2 (PPV2) defined as the number of cancers divided by number of biopsies indicated was 33% for DBT,
8% for BUS and 20,5% for DBT combined with BUS (figure 4)