Type:
Educational Exhibit
Keywords:
Lymphoma, Education and training, Developmental disease, Staging, Outcomes analysis, Comparative studies, PET-CT, MR, CT, Lymph nodes, Haematologic, Abdomen
Authors:
S. Jaimes Niño, L. K. Cifuentes Gaitán, D. L. Ochoa, D. Aguirre; Bogotá D.C., Bo/CO
DOI:
10.1594/ecr2018/C-0645
Background
The main objective of measurement scales to the response of the treatment is to standardize and simplify the radiological report,
to facilitate the evaluation of lymphomas and the analysis of clinic trials.
These guidelines are used in three key moments of the disease:
1.
Initial staging.
2.
Evaluation during treatment.
3.
Evaluation at the end of the treatment.
The Lugano classification is based on 2-fluoro-2-deoxy-D-glucose (FDG) positron emission tomography (PET-CT) or bidimensional tumor measurements on computerized tomography scans (CT).The main advantage of Lugano's classification is the use of PET-CT,
since this tool allows us to differentiate between viable tumor,
necrosis or fibrosis after therapy and differentiate progression-free survival between complete remission and partial response,
offering,
additionally,
great sensitivity to evaluate marrow compromise (even beyond the biopsy).
However,
the use of this guideline can be time consuming and has limited interobserver correlation (Fig.
3).
The RECIL scale comes from the need to facilitate the evaluation of lymphomas according to the response criteria in solid tumors (RECIST),
which is of vital importance in the oncology trials.
It is based on a single-dimension measurement of the tumor on CT.
The main disadvantage is that it does not take into account the behavior of the tumor in the PET-CT.