Keywords:
Abdomen, Liver, CT, MR, Contrast agent-intravenous, Haemangioma, Cirrhosis
Authors:
J. CHOI, J.-S. Yu, E.-S. Cho, J. H. Kim, J.-J. Chung; SEOUL/KR
DOI:
10.1594/ecr2018/C-0753
Results
For the 101 lesions,
the follow-up period ranged from 60 to 157 months (median,
81 months).
During the follow-up,
32 lesions (31.6%) and 21 lesions (20.8%) were enlarged and shrunken to >20% of the initial diameter,
respectively,
whereas 48 lesions (47.5%) showed no remarkable size change from 80% to 120% of the diameter (Table 1).
Only one patient (1%,
1 of 101) showed a remarkable (>20%) fluctuation in lesion size during the follow-up period (decrease in size from 1.7 to 1 cm during the first 5 years of follow-up,
and increase in size to 1.3 cm during the next 5 years),
and was categorized into the “shrunken” group.
The correlation coefficient between the patients’ age and the change ratios was -0.325 (p=0.001).
The mean ages of the three patient groups according to size change were 47.3 years (enlarged),
52.8 years (no change),
and 57.1 years (shrunken),
suggesting a higher tendency of lesion enlargement in younger patients (p=0.003).
In patients with liver cirrhosis (n=15),
seven lesions showed decrease in size,
seven lesions showed no change,
and one lesion was enlarged.
Patients with liver cirrhosis showed a significantly higher trend of lesion shrinkage than other patients (p=0.009).
The mean change ratio of hemangiomas in patients with a cirrhotic liver was significantly lower than in the remaining patients (0.865±0.679 vs.
1.146±0.459,
p=0.046).
Other factors including background fatty liver or drug history showed no statistical significance on univariate and multivariate analyses (p>0.05).
Logistic regression test showed that patients in the “shrunken” group were older in age (univariable,
p=0.017; multivariable,
p=0.046) than the remaining patients,
and the incidence of background cirrhosis was higher (univariable,
p=0.011; multivariable,
p=0.031) in these patients than in those in the “no change” and “enlarged” groups (Figure 2).