Type:
Educational Exhibit
Keywords:
Pathology, Neoplasia, Cancer, Biopsy, Ultrasound, MR, CT, Oncology, Musculoskeletal system, Musculoskeletal soft tissue
Authors:
J. L. VILLALOBOS FRANCO1, J. L. Villalobos juarez1, M. de los santos2; 1mexico city/MX, 2mexico/MX
DOI:
10.1594/ecr2018/C-0910
Background
This entity was first described in 1893.
It is considered a soft-tissue sarcomatous lesion,
which usually occurs in adolescents and young people,
which despite its name does not depend on intra-articular tissue,
but is close to an articulation.
It is the third sarcomatous lesion of soft tissue in the adult (1) it can be confused at first with benign lesions,
since they are small and painless lesions,
of slow growth,
in some cases they are associated with trauma (2)
Synovial Sarcoma,
mesenchymal neoplasm is clinically,
morphologically,
histologically and genetically is different from the rest of the sarcomas; with cytogenetic aberration t (X; 18) (p 11; q11) and the presence of translocations between SYT and the SSX genes (3).
The histological presentation has 3 types: A) Biphasic with spindle cells and epithelial cells (forming glandular structures) B) monophasic,
only with spindle cells and C) poorly differentiated epitheloid morphology and high mitotic activity (4).
Fusiform cells are distributed in fascicles with hyalinization and lobulation accompanied by mast cells,
bone or cartilaginous metaplasia and may have a hemangiopericytoid vascular pattern.
The undifferentiated or poorly differentiated type have a poor prognosis.
Of great importance are the studies of Immunohistochemistry.