Aims and objectives
Kidney biopsies have been performed over a century and percutaneous kidney biopsy (PKB) was introduced by Iversen and Brun at 1951.
(1,2) PKB is the gold standard procedure for the diagnosis,
guidance for treatment,
follow-up and prognosis for a variety of kidney diseases.
Complication rates and procedural success improved with technological advancements and improvements in technique.
Hematuria and perirenal hemorrhage are the most common complications of PKB (3).
Other complications include; AV fistula,
pseudoaneurysm,
urinoma,
need for blood transfusion,
embolization or nephrectomy.
In the literature,...
Methods and materials
Patient Selection
Two hundred and two biopsies between December 2012 and December 2016 were enrolled in this retrospective study.
Thirty-two biopsies were excluded because of missing data.
One hundred and seventy biopsies (including five transplants) were included in study.
Procedure Technique
Pre-procedural preparation includes written consent,
complete blood count (CBC),
coagulation profile.
PKB is an inpatient procedure at our center.
In patients younger than 13-year of age PKB is performed under sedation at our center.
Patients were placed in is prone position.
Fully automated 16...
Results
Results
Mean age was 12,04±5,15.
Ninety-eight (57,6%) of the patients were male and 72 (42,4%) were female.
Twenty-nine patients (17,1%) were between 0-6 years of age,
62 patients (36,5%) were between 7-12 years of age and 79(46,5%) patients were between 13-16 years of age. Thirty-six (21,2%) patients had acute renal failure at presentation.
Proteinuria was the most frequent biopsy indication (n=40,
23,5%).
Overall complication rate was 13,5% (n=23).
The most common complication was hematuria (n=10,
5,9%). Perirenal hemorrhage was seen in 8 (4,7%) patients.
Complications...
Conclusion
Overall complication rates of our study are consistent with the literature and BAPN recommendations.
US guided percutaneous renal biopsy is a safe and effective diagnostic tool for kidney diseases in pediatric patients.
Complication rates are higher in 13-16 age group.
The most common histopathologic results were IgA nephropathy,
FSGS and minimal change disease.
Acute kidney failure,
high creatinine and eGFR values were not associated with increased complication rates.
Personal information
Ruslan Asadov MD,Marmara University Hospital,Department of RadiologyFevzi Cakmak Mah.,
Muhsin Yazıcıoğlu Cad.
Pendik,
Ä°stanbul,
34899Fax: 0(216) 399 54 07
[email protected]
References
1.
Cameron JS,
Hicks J: The introduction of renal biopsy into nephrology from 1901 to 1961: A paradigm of the forming of nephrology by technology.
Am J Nephrol 17: 347–358,
1997
2.
Iversen P,
Brun C: Aspiration biopsy of the kidney.
Am J Med 1951;11:324–30
3.
Hussain F.,
Watson A.R.,
Hayes J.,
Evans J.: Standarts for renal biopsies: comparison of inpatients and day care procedures.
Pediatr Nephrol,
2003,18: 53-56.
4.
Tondel C,
Vikse BE,Bostad L,
Svarstad E.:Safety and complications of percutaneous kidney biopsies in 715...