Assessment of Severity of Portal Hypertension with Liver Cirrhosis based on the Attenuation Value in Abdominal Contrast Enhanced Multi-Detector-Row Computed Tomography

Congress:

ECR 2018

Poster Number:

C-1125

Type:

Scientific Exhibit

Keywords:

Cirrhosis, Diagnostic procedure, Contrast agent-intravenous, CT-Quantitative, CT, Liver, Abdomen

Authors:

Y. Inokuchi, S. Koya, M. Uematsu, T. Takashina ; Tokyo/JP

DOI:

10.1594/ecr2018/C-1125

DOI-Link:

https://dx.doi.org/10.1594/ecr2018/C-1125

Table 4: The attenuation value in each group.

Fig. 5: Box and whisker plot plot (10/90 Percentile) of the attenuation value...

Fig. 7: Graph show ROC curve for separating group A and B.

Fig. 9: Graph show ROC curve for separating group B and C.

Aims and objectives

The liver cirrhosis (LC) has various complications, and those disease has been greatly changed the prognosis of patients with LC [1-3]. Portal hypertension (PH) is regarded as the complication of LC, it is known that it is caused formation of collateral circulation [4]. As this principal mechanism, it is considered that increase of blood flow resistance accompanying the severity of hepatic fibrosis is a factor [4-6]. In the several previous studies at ultrasonography, the correlation between the hepatic vein arrival time and the severity of...

Methods and materials

Patients This study was approved by the relevant institutional review board, and the need to obtain informed consent from patients was waived for this retrospective study. We retrospective selected consecutive 55 patients with normal liver and 43 patients with LC who were ACE-MDCT for diagnosis of abdominal disease from February 2016 to January 2017. We excluded 10 patients with normal liver and 16 patients with LC. These patients had insufficient amount of contrast material dose (n = 7), imaging timing failure (n = 6), post...

Results

CT value of hepatic parenchyma in each group The mean and standard deviation of CT value in hepatic parenchyma of the portal phase and the equilibrium phase were 117.2HU ± 6.3 (range 96.7–125.6HU) and 95.1HU ± 4.4 (range 83.7–103.8HU), respectively in group A, 112.1HU ± 10.4 (range 93.4–127.8HU) and 96.5HU ± 6.6 (range 84.6-108.5HU), respectively in group B and 103.7HU ± 8.2 (range 89.3–118.4HU) and 93.4HU ± 5.3 (range 84.7–103.4HU), respectively in group C. The attenuation value in each group The mean and standard deviation...

Conclusion

This study assessed by using presence or absence of collateral circulation as the severity of PH [4-6], and indicated significant decrease of the attenuation value accompanying increase of the severity of PH with LC. In addition, we found the cut-off value to separate the severity of PH with LC. Therefore, the attenuation value is able to expected not only assessment of the severity of PH with LC but also as an indicator excluded development of collateral circulation. The patients with cirrhosis has been reported that...

Personal information

Yasuhiro Inokuchi, RT Department of Radiology, Edogawa Hospital, Tokyo, Japan; [email protected] Saki Koya, RT Department of Radiology, Edogawa Hospital, Tokyo, Japan. Masahiro Uematsu, RT,　 Department of Radiology, Edogawa Hospital, Tokyo, Japan. Tsuneyuki Takashina, MD Department of Radiology, Edogawa Hospital, Tokyo, Japan.

References

1. Sudhamshu KC, Matsutani S, Maruyama H et al (2006) Doppler study of hepatic vein cirrhotic patients: correlation with liver dysfunction and hepatic hemodynamics. World J Gastroenterol 12: 5853-5858. 2. Gines P, Fernandez-Esparrach G, Arroyo V (1997) Ascites and renal functional abnormalities in cirrhosis: pathogenesis and treatment. Baillieres Clin Gastroenterol 11: 365-385. 3. Salerno F, Guevara M, Bernardi M et al (2010) Refractory ascites: pathogenesis, definition and therapy of a severe complication in patients with cirrhosis. Liver Int 30: 937-947. 4. Bosch J, Pizcueta P,...