Type:
Educational Exhibit
Keywords:
Inflammation, Chronic obstructive airways disease, Computer Applications-Detection, diagnosis, CT-High Resolution, CT, Thorax, Lung, Computer applications
Authors:
G. Marrone1, F. Crinò1, S. Caruso1, A. Di Piazza1, G. Gentile1, V. Carollo1, G. Mamone2, M. Milazzo2, E. Oddo3; 1Palermo/IT, 2Palermo, It/IT, 3Palermo /IT
DOI:
10.1594/ecr2018/C-1416
Background
Cigarette smoke is a complex mixture containing more than 4000 compounds,
many of which have toxic effects both on the lungs and throughout the body.
The direct toxicity of cigarette smoke and the body's subsequent response to this lung injury leads to a wide array of pathologic manifestations and disease states that lead to both reversible and irreversible injury to the large airways,
small airways,
alveolar walls,
and alveolar spaces.
Besides chronic obstructive pulmonary disease,
pulmonary emphysema,
and lung cancer,
this group of diseases includes smoking-related interstitial lung disease (SR-ILD).
Interstitial lung diseases are a heterogeneous group of disorders characterized by damage to the pulmonary interstitial tissue,
dyspnea,
restrictive pulmonary function and impaired gas exchange.
High-resolution CT is highly sensitive in the detection of abnormalities in the lung parenchyma and airways.
The radiologist has to integrate the clinical findings and the pulmonary testing parameters with the HRCT imaging in order to make the right diagnosis and differentiating among the various entities.