Keywords:
Genital / Reproductive system female, Interventional non-vascular, Oncology, MR, Image manipulation / Reconstruction, MR-Diffusion/Perfusion, Biopsy, Structured reporting, Diagnostic procedure, Image verification, Pathology, Patterns of Care
Authors:
A. Malich1, A. Kott1, J. Feger1, D. Kovacevic1, I. papageorgiou1, U. K. M. Teichgräber2; 1Nordhausen/DE, 2Jena/DE
DOI:
10.1594/ecr2018/C-1607
Results
Histopathologic outcome of endorectyally performed MR-guided biopsy of the lesion was malignant in 108/205 lesions of the peripheral zone and 101/206 of the transitional zone.
Building two groups according to T2w-based scoring (1-3 predicitve for benignity; 4-5 predictive for malignany) the following results were obtained:
Sensitivity,
Specificity,
PPV,
NPV of T2w PIRADS at peripheral vs.
transitional zone were: 95.4%/95.0%; 22.7%/26.7%; 57.9%/55.5%; 81.5%/84.8%.
Taking into account S1-6 the data are:
Sensitivity:87.5%/88.0%/97.6%/97.1%/100%/100%; Specificity:28.6%/32.7%/25.3%/11.1%23.1%/12.5%;
The data yield to PPV and NPV (in all 6 size groups):
PPV:58.3%/55.7%/57.6%/57.9%/64.3%/66.7%;
NVP:66.7%/73.9%/92.3%/75.0%/100%/100%.
Size related accuracy was (S1-6): 58%;57%,62%,54%,62%,56%.
Consequently location is not crucial regarding the diagnostic power of T2w-based scoring of the lesions. Sensitivity increases with a cut off at 10mm largest diameter.