Aims and objectives
Pancreatic transplantation is currently the gold standardfor the restoration of the endocrine function(1).
The simultaneous pancreas-kidney transplant (SPK) is currently considered asthe best pre-terminal renal disease treatment for type 1 diabetic patients aged up to 55 and represents the main indication of pancreatic graft.Literature data show constant improvement of patient and graft survival,
as well as the superiority of this combined transplant to dialysis or tosingle kidney transplant,
particularly regardingthe long-term complications of diabetes(2-6).
Despite important advances in the selection of recipients and donors,
Methods and materials
This is a retrospective study of the whole population who underwent a pancreas transplantation in our University centre,
from April 2007 to December 2015.77 pancreatic transplants were conducted during this period.
The study of the clinico-radiological records included a total of 28 patients with early vascular thrombosiswithin the first month following transplantation.
Distal thrombosis of the pancreatic vessel transected margin or of the mesenteric artery stump or a margined thrombus with no reduction of the vessel lumen have beenconsidered criteriaof exclusion (Fig 2).
Among the 77 pancreatic transplanted patients in our Center,
18 presented significant thrombotic vascular complications.Thus the percentage of vascular complication on the overall transplanted population is 23.37%.Group T includes 8 patients (9.1% of the total number of pancreatic transplanted patients) and group NT includes 10 patients.
Comparison ofT and NT groups highlighted a significant differenceregarding cold ischaemia time,
whichwas higher ingroup T (p = 0.0308).There is also a non-significant trend regarding the recipients’ BMI,
whichwas more important in group T.At last,6 patients...
Our study has allowed to identify scanographic predictors of transplantectomy in a population of patients with thrombotic complications.These elements will provide the clinician with a support in his therapeutic orientation.We offer a radiologicalreading table and a diagram assimple prognostic tools to facilitate CT reading (fig 8,
2. Kelly WD,
Allotransplantation of the pancreas and duodenum along with the kidney in diabetic nephropathy.
Agence de la biomédecine - Le rapport annuel médical et scientifique 2015 [Internet].
[cited 2016 Dec 29].
Available from: https://www.agence-biomedecine.fr/annexes/bilan2015/donnees/organes/07-pancreas/synthese.htm
Long-term metabolic and quality of life results with pancreatic/renal transplantation...