Aims and objectives
Although studies have been performed on the epidemiology of Calcium Pyro-Phosphate crystalsdeposition disease (CPPD),
they have focused on articularinflammation occurrence with the radiographic determination of calcium deposition as a diagnostic criterion.
The aims of this study was to determine (a) the frequency of wrist chondrocalcinosis (CC) and CPPD arthropathy signs in a population of patients with no arthritis history and undergoing radiography (Rx) and (b) the association between these findings and wrist instability signs (scapholunate dissociation,
perilunate and lunate dislocation,
Methods and materials
This pilot single-center,
declaration of Helsinki-compliant study was approved by the institutional board and theinformed consent was waived.
Rx executed in Emergency Departmentbetween January 2015 and July 2017was retrospectively reviewed for the presence of CC and CPPD signs then the anatomy of the carpal bones was assessed.
X-ray of patients ˂18 years or inadequate was excluded.
The relationships among imaging findings,
age and sex were assessed with the t-test,
the Fisher’s exact test and logistic regression models as appropriate.
We examined 326 X-ray about 321 patients and we excluded 103 of them.
The overall prevalence of CC was 32.3% (72/223) and it increased with age (p <0.001,
In patients aged ≥60 years,
the frequency of CC was 58.2% (57/98).
The overall prevalence of wrist arthropathy was 29.6% (66/223) and it increased with age (p <0.001,
Exp(B)=1.034 (1.019-1.049)).In patients aged ≥60 years,
the frequency of arthropathy signs was 45.9% (45/98) and in patients ≥80 years: 45.5% (20/44).
there was a positive association...
CC and signs of CPPD arthropathy are seen with a high frequency in people with no history of arthritis and shows a positive correlation with age and carpal bones instability.
This data confirm the correlation of inflammatory arthropathy in patients with crystal deposition but also demonstrate the high frequency of this finding in general population clinically not affected by arthritis.
Institute of Radiology,
Department of Medicine,
University of Padua
ORCID ID: 0000-0002-8409-5603
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