Keywords:
Liver, Abdomen, Spleen, Elastography, Education, Cirrhosis
Authors:
I. Sporea, R. Sirli, R. Lupusoru, S. Nistorescu, C. Foncea, R. Mare, M. Danila, A. Popescu; Timisoara/RO
DOI:
10.1594/ecr2018/C-2469
Methods and materials
- Liver fibrosis is an important prognostic factor in chronic liver disease.
It's severity can be assessed invasively (by liver biopsy) or non invasively (by elastography or by biologic tests).
- According to EFSUMB guidelines [1] ultrasound based elastographic methods are divided into:
- Strain Elastography
- Shear Waves Elastography(SWE):
-Transient Elastography
-Point Shear Waves Elastography using ARFI technology (Virtual Touch Quantification- VTQ,
ElastPQ and Samsung)
-2D-Shear Waves Elastography (SSI,
GE,
Toshiba)
- Our study included 89 subjects with or without chronic liver disease,
in which liver stiffness (LS),
as a marker of fibrosis severity,
was evaluated in the same session by means of Transient Elastography (FibroScan,
EcoSens) and by a pSWE technique from Samsung (Medison RS80A Ultrasound Machine) (Fig1).
- Reliable LS measurements were defined for TE as the median value of 10 measurements with a success rate of more than 60% and an interquartile range/median ratio (IQR/M) less than 30%,
and for pSWE as the median value of 10 measurements with a reliability measurement index (RMI) of more than 0.5 and an IQR/M less than 30%.
- For classification of liver fibrosis severity we used TE as reference method with the following cut-offs: F2: 7kPa,
F3:9.5 kPa and F4: 12 kPa.
[2]