Keywords:
Embolism / Thrombosis, Computer Applications-3D, MR, Cardiac
Authors:
E. Glazkova, V. Makarenko, S. Alexandrova, M. Shlyappo; moscow/RU
DOI:
10.1594/ecr2018/C-2843
Methods and materials
Patient population
In this retrospective study,
15 patients were included: 8 healthy volunteers (28±11 years) and 7 patients with supraventricular arrhythmias,
paroxysmal form,
in sinus rhythm (35±8.5 years).
MRI protocol
All patients were studied with a 1.5 T MRI.
Cine 3D velocity-encoding acquisition was performed covering LA with ECG-gating.
Scanning parameters were: TR: 75-80ms; TE: 3,36ms; FA: 15°; venc: 80ms,
spatial resolution: 2,2x1,7x5mm.
Data Analysis
4D flow data were post-processed using 4D Flow version 2.4 (Siemens).
All 4 PVs ostia were selected at 3D model to define emitted planes and quantitative flow calculation.
(Fig.
1)
Visualisation of LA flow was performed by 3D color encoded particle traces emitted from defined planes for 1 cardiac cycle.
( Fig.
2) LA vortex flow was analyzed in the 3 functional phases of the LA cycle: reservoir,
conduit,
and pumping.
( Fig.
3)
Quantitative analysis of PVs consisted of measurement Peak velocity,
Peak volume flow rate,
Average volume flow rate and Forward flow rate.
Based on the data obtained simultaneously from 4 PVs of each patient,
PVs flow curves were constructed.
(Fig.4)
Statistical Analysis
The data presented as the median and interquartile range.
Nonparametric Mann–Whitney U test was used to determine the statistical significance of the differences found between the groups.
All tests used a significance level of 5% (<0,05).