Aims and objectives
The objective was to explore the value of computed tomography (CT) between the lesion and the surrounding normal liver parenchyma to differentiate the small hepatocellular carcinoma (SHCC,
≤ 3 cm) from the small hepatic focal nodular hyperplasia (SFNH,
≤ 3 cm) in the hepatic arterial,
portal,
and delayed phases.
Methods and materials
In this study,111 SHCC lesions in 108 cases and 36 SFNH lesions in 33 cases,
confirmed by clinically and/or pathologically,
were retrospectively analyzed.
All the patients underwent plain scan,
arterial phase (AP),
portal phase (PP) and delayed phase (DP) CT scans.
The lesions’ CT values (LCV) and the surrounding normal liver parenchyma (NCV) of the triple-phase enhanced CT scans (AP,
PP,
DP) were measured separately,
and the CT-value ratio = LCV/NCV was accordingly calculated.
The CT-value ratios of AP,
PP,
and DP were separately analyzed...
Results
The median age of 111 SHCC lesions in 108 patients and 36 SFNH in 33 patients was58 (51~64)vs.35(31~48)(P<0.01),the male/female ratios were(88vs.20)and(9vs.24) (P<0.01),and the size of the lesions was2.4 (1.8~3.0)vs.2.0 (1.5~2.88)(P= 0.12).
The CT-value ratios of the AP,
PP,
and DP of 111 SHCC in 108 patients and 36 SFNH in 33 patients were 1.43 (1.26 ~ 1.61) vs.
1.77 (1.63 ~ 1.90) (Z= -6.086,P<0.01),
0.84 (0.76 ~ 0.90) vs.
1.09 (1.03 ~ 1.16) (Z= -7.446,P<0.01),
and 0.79 (0.73 ~ 0.88) vs.
1.03 (1.00 ~ 1.06)...
Conclusion
The SHCC is highlysuggestedwhen the CT-value ratios of AP,
PP,
and DP are no more than 1.516,
0.949,
and 0.951,
respectively,
in the middle-aged and elderly male patients.
References
1.Ding J,Jing X,Wang Y,
et al.
Thermal ablation for hepatocellular carcinoma: a large-scale analysis of long-term outcome and prognostic factors.Clin Radiol,71(12)(2016),
pp.
1270-1276
2.
Hai-Tao Zhang,
Xin-Yi Gao,
Qin-Sha Xu,
et al.
Evaluation of the characteristics of hepatic
focal nodular hyperplasia: correlation between dynamic contrast-enhanced multislice computed tomography and pathological findings.
Onco Targets and Ther,
9 (2016),
pp.
5217-5224
3.Virgilio E,Cavallini M.
Managing Focal Nodular Hyperplasia of the Liver: Surgery or Minimally-invasive Approaches? A Review of the Preferable Treatment Options.Anticancer Res,38(1) (2018),
pp.
33-36
4....