Keywords:
Breast, MR-Diffusion/Perfusion, Diagnostic procedure, Cancer
Authors:
H. Caylak1, N. Köse1, S. Bulut2; 1SİVAS/TR, 2Sivas/TR
DOI:
10.26044/ecr2019/C-0471
Aims and objectives
Diffusion-Weighted Imaging (DWI) is a short,
non-contrast MRI method with the potential to increase specificity in addition to conventional breast MRI protocols (1,2).
The apparent diffusion coefficient (ADC) (Quantitative DWI) is a powerful imaging tool that provides unique information about the diffusion of water molecules in tissue,
predicting cellularity and structure (3).
In the clinic,
the current usage area of Breast DWI is to increase the accuracy of cancer diagnosis,
evaluate the effect of neo-adjuvant chemotherapy and guidance in the menagement of the treatment for cancer(4).
In many previous studies,
it has been shown that ADC is lower in malign breast lesions than benign lesions (2,4-10) . ADC measurements in breast lesions have not yet been standardized.
Different sizes and methods are used to place the Region of Interest (ROI).
The size and location of ROIs affect both ADC value and the reproducibility of measurements.
When more than one small ROI was used in the subregions where diffusion was most restricted to the whole tumor,
it was reported that the ADC values represent the most aggressive tissue component and leads to more accuracy in histopathological diagnosis (6).
The purpose of this study was to evaluate diagnostic accuracy of 1.5 Tesla DWI in differentiating malign breast lesions from benign lesions and compare the diagnostic performance of several small ROI (S-ROI) placed in the most aggressive subregions with a ROI (W-ROI) that covering the entire tumor.