Keywords:
Outcomes, Neoplasia, Cancer, Staging, MR-Diffusion/Perfusion, MR, Neuroradiology brain, CNS
Authors:
E. Soligo1, S. Gangi1, A. Trisoglio1, S. Berardo2, L. SUKHOVEI 1, A. Stecco1, A. Carriero3; 1Novara/IT, 2Novara, Italy/IT, 3Novara (NO)/IT
DOI:
10.26044/ecr2019/C-0871
Aims and objectives
Actually maximal surgical resection of glial neoplasia,
in our study in particular we studied a subgroup of neoplasias such as "Glioblastoma Multiforme",
presents the most import prognostic value.
MRI is important to distinguish,
performed after surgery,
"reactive impregnation",
non-neoplastic and due to the surgical manipulation of the brain,
and "nodular impregnation",
neoplastic to plan appropriate therapies and to properly monitor the response to those.
Differential diagnosis between both is a challenge: studies have focused on the time to perform postoperative radiological investigation.
In the study of Albert et al.,
performed at 1.5 T,
didn’t observe benign contrast enhancement in the first 4 post-surgery days and on these findings they recommended to perform MR within 72 hours after surgery,
before the appearence of reactive changes.
However a growing number of studies proved that a "reactive impregnation" might appear earlier than 72 hours.
The aim of our work was tried to find a more accurate time window to perform MRI protocol after brain resection of glioblastoma: in order to discriminate early postoperative changes from residual neoplastic tissue.