Keywords:
Tissue characterisation, Lymphoma, Image verification, Staging, Diagnostic procedure, Comparative studies, PET-CT, MR-Diffusion/Perfusion, Oncology, Radiation physics, MR physics
Authors:
K. Matera, D. Baranska, M. T. Podgórski, M. Górska-Chrząstek, K. Krajewska, J. Trelińska, P. Grzelak; Łódź/PL
DOI:
10.26044/ecr2019/C-1156
Results
All patients were diagnosed with multiple locations of neoplastic process (median number of 16 locations,
range 7-26).
All regions of increased metabolism visible in 18F-FDG PET/CT presented decreased diffusion in DWIBS (Fig.
2).
Fig. 2: Images of a 14-year-old girl with Hodgkin lymphoma. a- 18F-FDG PET/CT (coronal WB), b- WB MRI, coronal MIP reconstruction of STIR shows enlarged lymph nodes with high signal intensity c- 18F-FDG PET/CT (with scale of glucose metabolism intensity) images showing 18F-FDG uptake (arrow) of cervical region; d- WB MRI, axial of b800-weighted DWIBS image subtraction showing lymph nodes (arrow) with restricted diffusion.
References: Department of Diagnostic Imaging, Polish Mother's Memorial Hospital- Research Institute in Lodz/ Poland 2018
Moreover,
values of ADCmean and SUVmax correlated significantly with each other (R2 = - 0.36; p = 0.0002) (Fig.
3).
Fig. 3: Scatter diagram of association between ADCmean and SUVmax values.
References: Department of Diagnostic Imaging, Polish Mother's Memorial Hospital- Research Institute in Lodz/ Poland 2018
In addition,
33 regions with restricted diffusion were not recognized in 18F-FDG PET/CT.
These regions were significantly smaller (35.2,
SD=30.9 mm2) than localizations visible in both techniques (86.2 SD=70.3 mm2) (p=0.0001).
There was a significant negative relationship between the lymph node area and the ADC value,
which is confirmed by the Spearman’s rank correlation coefficient (R2 = -0.321,
p <0.001).