Keywords:
Outcomes, Infection, Acute, Outcomes analysis, CT-High Resolution, CT, Conventional radiography, Thorax, Lung
Authors:
K. Schoen1, N. Horvat2, N. F. C. Guerreiro2, I. de Castro2, K. Giassi2; 1São Paulo, Paraná/BR, 2Sao Paulo/BR
DOI:
10.26044/ecr2019/C-1732
Aims and objectives
Influenza A H1N1 virus is the subtype of influenza virus that typically leads to a more severe infection than the usual seasonal influenza virus.
It was the cause of the last influenza global outbreak in 2009,
which resulted in thousands of deaths worldwide,
principally among young individuals and pregnant woman.
Since then,
the H1N1 influenza virus has assumed a seasonal spreading similar to other influenza types and continues to cause substantial morbidity, although it is controlled with the immunization programs.[1] Nevertheless,
an atypical outbreak occurred in South America in 2016,
which started before the vaccination campaign,
and caused approximately 800 deaths and 500 intensive care unit internments in a single country.[2]
Since the first outbreak of H1N1,
many studies have been conducted to identify an imaging pattern [3,
4] or clinical features that indicate a worse prognosis.[1,
5,
6] The identification of clinical and radiographic findings in patients with H1N1 infection that correlate with the clinical severity is of key importance in the management of these patients.
Previous studies have demonstrated that all patients with H1N1 admitted to an intensive care unit had at least an abnormal CR at diagnosis.
However,
there is a relative lack of studies in the literature that have examined predictive tools in the evaluation of patients with H1N1.[7,
8]
In this scenario,
the purpose of this study was to evaluate the correlation between clinical and imaging findings with a worse clinical outcome in patients with a confirmed diagnosis of H1N1 influenza A virus.