Keywords:
Inflammation, Infection, Outcomes analysis, PET-CT, Hybrid Imaging
Authors:
S. Nausheen1, S. Hamid1, S. Baber1, S. Kadri2, N. Ahmed1, T. Mahmood1; 1Karachi/PK, 2Karachi, karachi/PK
DOI:
10.26044/ecr2019/C-1936
Results
Total 31 patients were evaluated with PET scan for the diagnosis of fever of unknown origin.
16 were males and 15 were females with age ranges between 18 to 72 years with mean age 38 years.
Out of 31,
25 were PET scan positive, 24 were true positive and accurately contribute in diagnosis while 01 patient was false positive. 06 patients were PET negative,
out of which 03 were true negative and 03 were false negative.
PET/CT showed sensitivity and specificity 88.8% and 75% respectively.
Positive pridictive value 96% and negative pridictive value 50% with diagnostic accuracy 87% Results are significant at p value <0.05
Out of 25,
11 were of infective,
09 were diagnosed as suspicious malignant etiology and suggest the site of biopsy,
for example one patient was of neurofibromatosis with multiple neurofibromas and increase FDG uptake in chest wall neurofibroma raises the suspicioun of malignancy,
which later prove on histologically. 05 patients were diagnosed as inflammatory disorder out of which 01 case was of aortitis and 01 was of mesenteric adenitis and 01 patient reveals tracer uptake in marrow and diagnosed as myeloprolifetrative disorder confirmed on marrow biopsy.
Comparison done with other studies like Anuratha-et-al calculate sensitivity 90.9% and specificity 66.67% on data of 25 patients (2) Bleeker Rovers-et-al calculate sensitivity and specificity of 88% and 77% respectively on data of 35 patients.
(3) Keidar et al prospectively studied role of PET CT in 48 FUO patients and showing the sensitivity 100% and sepcificity 81% (4) Nurhan et al calculate sensitivity 92 % and specificity 45% (1)