Keywords:
CNS, Neuroradiology brain, Oncology, MR, MR-Diffusion/Perfusion, MR-Functional imaging, Radiation therapy / Oncology, Chemotherapy, Cancer, Neoplasia, Radiation oncology in Developing Nations
Authors:
K. Kenigsberg; Minsk/BY
DOI:
10.26044/ecr2019/C-2469
Aims and objectives
Glioblastoma nowadays is still one of the most malignant brain tumors with low median overall survival of 14-18 months [1].
Standart treatment is surgery followed by chemoradiation.
Evaluation of tumor progression on MRI is often made with RANO Criteria based on measurements of tumor size on contrast-enhanced T1W.
However,
with advanced techniques there are options to measure tumor perfusion characteristics with DSC,
DCE or ASL techniques,
tumor cellularity with DWI,
vascular architecture with SWI,
TOF and post-contrast T1W,
etc.
This techniques could possibly provide the useful for prognosis information on earlier followup period that is recommended by RANO [2].
Despite the low overall survival,
under the date of some authors about 10% of patients with glioblastoma survive for more than 5 years [3].
Dealing with glioblastoma patients we've found several possible anatomic markers of early disease progression,
among which there is a tumor invasion of lateral ventricle choroid plexus.
The aim of this study is to clarify whether invasion of choroid plexus (CP) by glioblastoma during postoperative treatment results early progression of the disease.