Keywords:
Infection, Diagnostic procedure, CT, Thorax, Respiratory system, Lung
Authors:
S. Kim, H. N. Lee, H. J. Koo, S. H. Choi, H. Sung, K.-H. Do; Seoul/KR
DOI:
10.26044/ecr2019/C-2774
Conclusion
HBoV infection can cause respiratory infections in adults and is associated
with a high incidence of pneumonia,
especially in nosocomial and older patients. Although neutropenia and lymphopenia were not significant risk factors for pneumonia in this study.
The overall mortality rate of HBoV infection at 30 days(7.6%) was similar with those for other respiratory viral infections,
such as human metapneumovirus and RSV,
in adult patients (7-8%). Whereas HBoV infections in children showed a less severe disease course than RSV infections.
The predominant CT findings of HBoV pneumonia were bilateral consolidation and GGOs. We found that HBoV pneumonia usually showed bilateral areas of consolidation and GGO with interstitial thickening,
and centrilobular nodules were less frequently observed,
which suggests a dominant interstitial parenchymal pattern rather than an airway-centric pattern. The extent of consolidation was larger in immunocompromised patients.
These data emphasize that HBoV is one of the critical respiratory pathogens in adults,
and more extensive epidemiologic studies with adult patients may be beneficial.