Keywords:
Interventional non-vascular, Oncology, Pelvis, Ultrasound, Percutaneous, Ablation procedures, Neoplasia, Metastases
Authors:
M. H. A. F. Shaaban1, M. F. Tolba2, R. H. Hashem2; 1Cairo , Maadi/EG, 2Cairo/EG
DOI:
10.26044/ecr2019/C-3744
Methods and materials
18 patients diagnosed with inoperable locally advanced pancreatic cancer ,
8 patients with hepatic malignancies reaching the liver capsule,
(size range 2-5 cm ),
2 patients with aggressive fibromatosis in the lower limbs , 2 patients with retroperitoneal malignant masses (leiomyosarcoma and metastatic lymph nodes ,
1 patient with hemipelvic bony metastatic cancer breast ,
2 patients with metastatic rib from HCC,
6 patients with adenomyosis (2 focal ,
4 diffuse) .
They all underwent US guided HIFU treatment aiming control of pain .
HIFU was focused on the presumed site of the source of pain nerve endings ,
at the lesion periosteum interface in bony lesions.
The primary outcome measures pain severity in all patients and daily opioid consumption in cancer patients .
Pain was assessed on a 100 mm visual analogue scale (VAS).
The daily opioid consumption was calculated as morphine sulphate equivalence; daily morphine consumption (DMC).
The secondary outcome measures in all patients were quality of life and the degree of disability,
and procedure related adverse outcomes.
The quality of life was assessed using the Patient’s Global Impression Of Changes (PGIC).
The degree of disability was assessed using the Oswestry Disability Index (ODI).
The outcome measures were assessed in the preoperative visit,
and 1 week,
4 weeks and 12 weeks after the procedure