The value of SeHCAT scans in diagnosing bile acid malabsorption (BAM) as a cause of chronic diarrhoea following pelvic radiotherapy treatment (PRT).

Congress:

ECR 2020

Poster Number:

C-00070

Type:

Educational Exhibit

Keywords:

Performed at one institution, Observational, Retrospective, Cancer, Radiation therapy / Oncology, Radiation effects, Nuclear medicine conventional, Oncology, Nuclear medicine, Oncologic Imaging

Authors:

V. M. Rhodes¹, T. Toma²; ¹Southend/UK, ²SOUTHEND ON SEA/ESSEX/UK

DOI:

10.26044/ecr2020/C-00070

DOI-Link:

https://dx.doi.org/10.26044/ecr2020/C-00070

Fig. 1: Fig 1. This image demonstrates the field of view for a prostate cancer patient...

Fig. 2: Fig 2 and 3. Extent of the radiation field of view for a gynaecological...

Fig. 3

Learning objectives

Our aim is to identify the percentage and severity of BAM in patients with pelvic radiotherapy treatment following a diagnosis of prostate, gynaecological or bowel cancer.

Background

SeHCAT scans have been used since the early 1980’s to diagnose bile acid malabsorption (BAM). Since then the frequency of referrals for SeHCAT scans has continued an upward trend as BAM has become increasingly recognized as an important cause of severe chronic diarrhea. (Stacey et.al 2015) Pelvic radiotherapy treatment has been used as an effective cancer treatment for many years. However although PRT maybe successful at treating the cancer, it is impossible to prevent collateral damage to the surrounding healthy tissue. This damage can then...

Findings and procedure details

Method. A retrospective analysis of SeHCAT scans under taken within a 24 month period identified 38 out of a total of 403 scans that had undergone pelvic radiotherapy treatment. Our analysis focuses on these 38 patients. From these it was found that there were 20 males diagnosed with prostate cancer, 12 females with gynaecological cancer and 6 patients with bowel cancer. All patients received radiotherapy treatment following the national guidelines.

Conclusion

Results and Conclusion The results of this retrospective study show that the prevalence of BAM in patients who have under gone pelvic radiotherapy treatment is as follows: The results presented show that: For Prostate Cancer 55% of patients had normal SeHCAT scan results and 45% of patients presented with BAM. For Gynaecological Cancer 8% of patients had normal SeHCAT scan results and 92% of patients presented with BAM. For Bowel Cancer patients 33% of patients had a normal SeHCAT scan result and 67% of patients...

Personal information and conflict of interest

V. M. Rhodes; Southend/UK - nothing to disclose T. Toma; Southend on Sea/Essex/UK - nothing to disclose

References

Stacey R, Cox B, Turner J, et al PTU-325Developing a pelvic radiation disease service – which patients do we see in a regional secondary care centre? Gut 2015;64:A204-A205 Phillips, F., Muls, A.C.G., Lalji, A. and Andreyev, H.J.N. (2015), Are bile acid malabsorption and bile acid diarrhoea important causes of loose stool complicating cancer therapy?. Colorectal Dis, 17: 730-734.