Keywords:
Neuro, Computer applications, Head and neck, Neuroradiology brain, MR, MR-Functional imaging, Neural networks, Computer Applications-Detection, diagnosis, Experimental investigations, Drugs / Reactions, Education and training, Prospective, Experimental, Performed at one institution
Authors:
J. fan, J. Liu; NanJing/CN
DOI:
10.26044/ecr2020/C-01617
Conclusion
We found distinct differences in brain activations in fronto-parietal network between two groups [differing neural activation in the left Inferior parietal gyrus (1back-0back) and the cingulate gyrus、parietal lobe、frontal lobe、precuneus (2back-0back)].The prefrontal cortex plays an indispensable role in improving N-back task performance, by selecting proper high-level organizational chunks to reduce the cognitive load thereby enhancing working memory. Thus,This region may serve to the strategic control of WM.The precuneus, which we found to be affected during 2back-0back condition, is known to be involved in episodic memory retrieval– also necessary for WM performance tasks[1]. The left posterior parietal cortex ,which we found during 1back-0back condition is activated whenever short-term storage of verbal memory is required. This involvement may be as part of a circuit mediating shifts of attention critical for verbal rehearsal or may be part of a circuit involving storage itself[2]. Activation in the inferior parietal cortex has been found frequently in contrasts of working memory load (e.g., number of items) where needs high attention . Thus the left precuneus and left posterior parietal cortex - which we found to exhibit altered activation patterns in our n-back condition - are known to be associated with short-term storage of verbal memory ,high attention and retaining temporal information.Besides,we also found different neural activation in the cingulate gyrus,which may be associated with the monitoring of errors and conflicts.Moreover,performance in association with the PFC is also adjusted by cingulate gyrus [3-5].Thus,NBCCR may mediate fronto-parietal network to improve working memory in depressed patients.