Keywords:
MRI, Contrast agents, Liver, MR physics, MR, Contrast agent-intravenous, Quality assurance, Retrospective, Not applicable, Performed at one institution
Authors:
A. Pratesi1, S. Covizzoli2, S. Chiti2, D. Ermini2; 1Siena/IT, 2Florence/IT
DOI:
10.26044/ecr2020/C-06298
Purpose
Gadoxetate disodium is an MRI paramagnetic contrast agent that allows a dynamic liver study like a “traditional” contrast medium, while at the same time enabling the study of hepatobiliary phase and providing information on hepatocyte uptake. Due to reduced dose of administration compared to a traditional contrast medium (0.1 ml/kg vs 0.2 ml/kg), and to reduced content of gadolinium (0.025 mmol/ml vs 0.1 mmol/ml) [1], amplitude and duration of enhancement peak can be reduced, making it difficult to synchronize the acquisition and the passage of the bole [2][3]. We chose to engage in this study because the arterial phase, which is fundamental for visualization, characterization and assessment of the response to possible treatment of focal liver lesions, is often of insufficient quality and compromised by the presence of truncation artifact due to medium agent variation during K-Space filling. The artifact manifests itself during arterial phase with hyper and hypointense lines around impregnated organs. The aim of this work is to analyze the artifact and find solutions to improve the quality of the arterial phase.