Keywords:
Cardiac, Cardiovascular system, Foetal imaging, Obstetrics (Pregnancy / birth / postnatal period), Ultrasound-Colour Doppler, Ultrasound-Power Doppler, Ultrasound-Spectral Doppler, Observer performance, Outcomes analysis, Foetus, Obstetrics, Prospective, Case-control study, Performed at one institution
Authors:
A. Damodaran Nampoothiry1, P. D. J. Deevimeenal2, K. Gopinathan2, D. K. GEETHA2, D. B. Y. Akash Kumar2, R. Prasan2; 1Chennai, Tamil Nadu/IN, 2Chennai/IN
DOI:
10.26044/ecr2020/C-07423
Methods and materials
Patient population
44 pregnant women (ages 18 – 35, mean age 26) at 28-38 weeks with either pregestational or gestational diabetes and with no other systemic or pregnancy related disorders were compared with 44 gestational age matched healthy controls by using fetal left ventricular MPI from July 2018 to June 2019.
Inclusion criteria included pregnant women at 28-38 weeks of gestation with pregestational/gestational diabetes mellitus.
Exclusion criteria were maternal anaemia, preeclampsia, multiple pregnancies, IUGR, congenital anomalies.
Data Acquisition – Ultrasound examination was done using GE Voluson E6. The Mod-MPI was obtained in either apical or basal four chamber view and the spectral Doppler sample volume was placed in the lateral wall of aorta, close to the mitral valve, with the transducer slightly cranially displaced to visualize the mitral and aortic valves. Fig. 2
Fig. 2: Spectral Doppler sample volume was placed on the lateral wall of the ascending aorta, below the aortic valve and just above the mitral valve
All patients in the study group were followed for diabetic control and also for foetal wellbeing. An adverse perinatal outcome was defined by any one of the following: respiratory distress, hyperbilirubinemia, reduction in APGAR score, cord PH
Data collected were entered into excel sheet and statistical analysis was performed with SPSS version 21.0. The parametric data was appraised using independent students t test and comparison of percentages were done using chi-square test. Receiver operating characteristic analysis was used to evaluate the predictive performance of MPI for adverse perinatal outcomes. P value