Keywords:
Cardiac, CT-Angiography, Computer Applications-Detection, diagnosis, Ischaemia / Infarction, Retrospective, Observational, Performed at one institution
Authors:
M. Kawakubo1, M. Nagao2, K. fukushima3, E. Watanabe2, A. Sakai2, S. Suzaki2, Y. Shimomiya2, S. Sakai4; 1Fukuoka/JP, 2Tokyo/JP, 3Saitama/JP, 4Shinjuku-ku, Tokyo/JP
DOI:
10.26044/ecr2020/C-08952
Purpose
Coronary computed tomography angiography (CCTA) is a clinically reliable method for detecting coronary stenosis for the patients with coronary artery disease (CAD) [1, 2]. However, the presence of coronary stenosis is not necessarily image findings which indicate the functional stenosis [3]. Therefore, adenosine-stress myocardial perfusion scintigraphy (MPS) have been conventionally played a major clinical role for the diagnosis of the functional coronary stenosis. Recently, to overcome the invasiveness of MPS, fractional flow reserve computed tomography (FFR-CT) which invasively simulate coronary hemodynamics is proposed and applicated in clinical location [4]. Also, a novel method named computed tomography instantaneous wave-free ratio (CT-iFR) has been proposed to measure rather than estimate coronary hemodynamics [5]. In this method, it is concern that the radiation exposure will increase because the whole heart dynamic scan is performed while the contrast agent is injected, but this has been successfully resolved by dose modulation during scan and noise reduction by image post-processing. In the present study, the diagnostic performance for functional coronary stenosis of CT-iFR was compared to the conventional CCTA.