Keywords:
Cardiac, CT-Angiography, Computer Applications-Detection, diagnosis, Ischaemia / Infarction, Retrospective, Observational, Performed at one institution
Authors:
M. Kawakubo1, M. Nagao2, K. fukushima3, E. Watanabe2, A. Sakai2, S. Suzaki2, Y. Shimomiya2, S. Sakai4; 1Fukuoka/JP, 2Tokyo/JP, 3Saitama/JP, 4Shinjuku-ku, Tokyo/JP
DOI:
10.26044/ecr2020/C-08952
Conclusion
CCTA has traditionally made a significant contribution as a screening tool with high negative predictive value for coronary stenosis [8, 9]. Furthermore, in recent years, CT imaging is expected to be a new four-dimensional diagnostic tool such as CT-FFR with the advance of CT equipment and computers. Our proposed CT-iFR can be calculated in not only coronary distal site but also any coronary site. It is effective for clinical use to display as the color coded image as shown in Figure 5. Also, image processing techniques such as iterative reconstruction and motion coherence image processing can be expected to make CT imaging less invasive. There is also a report that a dynamic scan similar to this study was performed with an effective radiation dose of 4.1 mSv [5]. Moreover, since CT-iFR is continuous data, it may be applicable not only to ischemia diagnosis like MPS but also to ischemia grading. Consequently, in the future, CT imaging is expected to be a definitive tool for diagnosing ischemia instead of MPS. This study at least shows that CT-iFR diagnoses functional ischemia with higher accuracy than conventional CCTA, and we believe that it will provide basic evidence for the future development of CT imaging.
In conclusion, CT-iFR derived with dose modulated dynamic imaging accurately detect myocardial ischemia, and would promise less invasively assessment of the not anatomy but functional coronary stenosis.