Keywords:
Performed at one institution, Observational, Retrospective, Inflammation, Calcifications / Calculi, Drainage, Ultrasound, Fluoroscopy, Interventional non-vascular, Biliary Tract / Gallbladder, Abdomen, Abdominal Viscera
Authors:
S. Schiro', A. Andreone, I. Paladini, E. Epifani, C. Marcato, N. Sverzellati; Parma/IT
DOI:
10.26044/ecr2020/C-10134
Methods and materials
All patients with acute cholecystitis who underwent US-guided percutaneous cholecystostomy (PC) between 2013 and 2018 in a single center were retrospectively reviewed.
Detailed information was collected on:
- comorbidities (cardiovascular, neurological, respiratory and renal dysfunction);
- clinical symptoms;
- laboratory values (WBC, CRP);
- prior-PC imaging.
The imaging studies performed prior-PC included Ultra-Sound (US) and Computed Tomography (CT). Concerning prior-PC imaging, the following findings were recorded: one or more gallstone(s), distended gallbladder, edematous gallbladder, ruptured gallbladder, pericholecystic fluid, positive US Murphy's sign.
Laboratory values (WBC; CRP) were retrospectively collected through digital clinical records. Where available we collected the results of these investigations performed prior and after PC [1].
Clinical, laboratory values and imaging findings were used to grade the participants into mild, moderate and high risk patients according to 2018 Tokyo Guidelines (TG18) Table 1. [2,3].
Only moderate and high risk patients (TG18 II-III), were included in the study.
Detailed participants selection is shown in Fig.2.
Mortality and cholecystectomy (CH) within 30 days from the PC were recorded.
Primary outcome was relief of acute symptoms and decrease of laboratory values.
Linear regression analyses were performed to assess the association between PC or PC+CH with primary outcome.
Pearson’s Chi squared test was performed to assess differences in patient and prior-procedure imaging characteristics between those treated exclusively with PC and those treated with PC+CH.