In the brain, the study of gray matter, and in particular of cortical organization, is facilitated by the presence of fissures and sulci along its surface which divide it into lobes and gyri [1]. The detailed evaluation of the structure of the White Matter (WM), on the other hand, is more demanding as it does not present anatomical reference points except for the contours outlined by the adjacent structures, such as the cortical structure, ventricles and basal ganglia [2-4]. However, the WM contains fibers with...

Clinical Study: In this prospective study four patients with primary or secondary brain diseases were involved (table 1). MRI Equipment: To perform the magnetic resonance examination, a tomograph consisting of a superconducting magnet generating a 1.5 Tesla static magnetic field was used.An 8-channel Phased Array SENSE volumetric radio frequency coil was used to carry out head examinations. Preliminarily, the neuroradiologist obtains informed consent from the patient to perform an MRI and to administer contrast medium. Subsequently, the subject was placed in supine position on the...

For each patient we compared the "standard" treatment plan (without CST information) with the "fiber info" treatment plan (including CST information) using the distribution of isodose and Dose-Volume Histogram (DVH). DVH is a graphical representation of the dose received by normal tissues and target volumes within a radiotherapy plan. It provides information on the volume of a structure receiving a given dose over a range of doses [11]. First Patient: CST information has allowed a reduction of the maximum dose by 13% and a reduction...

Stereotactic radiotherapy is widely recognized as an effective treatment modality in the management of various intracranial lesions [12]. However, the damage caused by ionizing radiation from this therapy on all the OARs surrounding tumor targets should not be underestimated. The main objective is therefore to increase the biological efficacy of the treatment and safeguard the patient from potential side effects resulting from radiotherapy damage to the motor pathways. A reduction of up to 70% of the dose received by the CST beam was obtained, thus...

M. Vertuani; Ferrara/IT - Author at AOU Arcispedale S. Anna of Ferrara - Speaker at AOU Arcispedale S. Anna of Ferrara S. Ceruti; Ferrara/IT - Author at AOU Arcispedale S. Anna of Ferrara L. Manco; Modena/IT - Author at AOU Arcispedale S. Anna of Ferrara

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