Learning objectives
To demonstrate normal anatomy and relationship of fetal corpus callosum.
To obtain ‘virtual’ mid-sagittal plane images reconstructed from an axial approach using 3D imaging techniques like VCI (Volume Contrast Imaging) and Omni View.
To illustrate indirect signs of agenesis of corpus callosum.
Background
The corpus callosum represents largest commissure connecting the two cerebral hemispheres. It develops relatively late during cerebral ontogenesis, not assuming its definitive shape until 20 weeks of gestation, and continues to grow well after delivery. Therefore, a proper prenatal sonographic evaluation can be performed only after 20 weeks. The development starts from anterior and then continues posteriorly.
The prevalence of corpus callosum anomalies varies significantly in the different studies, depending on the population and the diagnostic criteria: it ranges from 0.3–0.7% in the general population...
Findings and procedure details
Most of the images were obtained by standard transabdominal approach only however, in vertex fetal presentation, a transvaginal scan with a high-frequency transducer provides better resolution.
2D Dimensional approaches for visualization of corpus callosum are fetal profile approach and Coronal approach.
Addition of colour Doppler helps in delineation of normal course of pericallosal artery which highlights the corpus callosum. The abnormal course pericallosal artery means that it repeats the contour of the preserved parts of the corpus callosum and rises upwards at the level of...
Conclusion
In addition to routine 2D US, 3D ultrasound techniques like VCI mode and Omniview technology has advantages of obtaining more effective and better quality of corpus callosum images which enhances confidence in making diagnosis of partial or complete agenesis of corpus callosum.
Personal information and conflict of interest
M. Jadhav MD DNB;Adi advanced fetal centre for fetal care,Banglore/IN-nothing to disclose.
A. Makam MD FRCOG; Adi advanced fetal centre for fetal care,Banglore/IN-nothing to disclose.
P. Agrawal DGO DNB; AAdi advanced fetal centre for fetal care,Banglore/IN-nothing to disclose.
R. Sanghani DGO; Adi advanced fetal centre for fetal care,Banglore/IN-nothing to disclose.
S. Masudi MD;Adi advanced fetal centre for fetal care,Banglore/IN-nothing to disclose.
References
Youssef, T. Ghi and G. Pilu How to image the fetal corpus callosum Ultrasound Obstet Gynecol 2013; 42: 718–720
Dario Paladini, Paolo Volpe, Ultrasound of Congenital Fetal Anomalies Textbook, Pages-26 -31
O. I. Kozlova1, M., Medvedev1, E. D. Lutaya2, Y., Shatokha1, N. A. Altynnik1 Prenatal Ultrasound Diagnosis of Agenesis of the Corpus Callosum: Analysis of 34 Cases J. Pharm. Sci. & Res. Vol. 10(10), 2018, 2534-2536