Keywords:
Cardiac, Haematologic, Pancreas, MR, Outcomes analysis, Statistics, Haematologic diseases, Not applicable, Diagnostic or prognostic study, Multicentre study
Authors:
G. Peritore1, A. Meloni2, L. Pistoia2, N. Giunta1, M. G. bisconte3, V. Positano2, D. Messana1, A. Pepe1; 1Palermo/IT, 2Pisa/IT, 3Cosenza/IT
DOI:
10.26044/ecr2020/C-11050
Results
Global pancreas T2* values were not correlated to age or gender. Ninety patients (58.1%) showed a pathologic pancreas T2* value (< 26 ms) (Fig.1).
One-hundred and five patients were transfusion dependent and they showed significantly lower global pancreas T2* values than non-transfusion dependent patients (19.82±12.62 ms vs 28.52±10.81 ms; P<0.0001) (Fig. 2) and a significant higher frequency of pathologic global pancreas T2* value (66.7% vs 38.8%; P=0.001).
A significant correlation between pancreatic and cardiac T2* values was detected and (R=0.194; P=0.015) and all the five patients with Myocardial Iron Overload (global heart T2*<20 ms) had also pancreatic iron load (Fig.3).
Global pancreas T2* values were not correlated to biventricular volumes and ejection fraction and no association was detected even in the subgroup of transfusion dependent patients.
LGE sequences were acquired in sixtyfour Thalassemia Intermedia patients and seventeen (26.6%) of them showed macroscopic myocardial fibrosis. Global pancreas T2* values were comparable in patients without and with fibrosis (24.37±11.65 ms vs 25.75±14.32 ms; P=0.574).