Lung cancer is the most common cause of cancer mortality in the world [1]. Moscow Lung Cancer Screening project was launched in Moscow since 2017, aimed at the selective screening of lung cancer in an outpatient population through the use of ultra-low-dose computed tomography (ultra-LDCT). It should be noted that several similar screening projects are currently being carried out in the world, which has proved their importance in increasing early detection and reducing mortality [2]. Along with lung nodules, according to the ultra-LDCT, it is...

Patient population: During the baseline round of screening, 4762 ultra-LDCT (individuals who met the inclusion criteria for the lung cancer risk group) were performed in 10 medical organizations that provide primary health care to the adult population in Moscow. The studies were performed on a 64-detector unit using specially developed ultra low dose protocols for different patient weight categories with a radiation dose of up to 1 mSv. Data acquisition: The study included 254 (4.78%) ultra-LDCTs, which were selected using a random number generator. The...

The localization of incidental findings was as follows (Fig.1 and Fig.2): lungs and bronchi - 68.5%, pleura - 2.75%, cardiovascular system - 76.4%, mediastinum - 2.75%, abdominal cavity (upper abdomen) and retroperitoneal space - 4.2%, organs of the endocrine system - 2.7%, mammary glands - 0.8%. A total of 58.4% of incidental findings were not reported in the original protocols of the ultra-LDCT studies. In the initial ultra-LDCT report, radiologists would often mention adrenal lesions (3 cases, not indicated 100.0%), pulmonary trunk dilatation (19 -...

1. During the implementation of selective lung cancer screening with ultra-LDCT, incidental findings occur in 87.5% of cases. Most often they are localized in the cardiovascular (76.4% ‒ 169) and respiratory (68.3% ‒ 151) systems. 2. Prevalence and nature of incidental findings detected during screening with ultra-LDCT, indicate that in most cases, such findings have high clinical or prognostic significance. Calcification of the coronary arteries ‒ 69.6% (154), thickening of the bronchi walls ‒ 40.2% (89), bronchiectasis ‒ 40.2% (89), emphysema ‒ 24.8% (55). 3....

Mr. Alexander Nikolaev, MD Scientific Practical Clinical Center of Diagnostics and Telemedicine Technologies, Moscow Health Department, Moscow, Russia Phone: +79303483048 e-mail: [email protected] Mr. Dr. Ivan Blokhin Author: Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of Moscow Health Care Department Mr. Dr. Victor Gombolevskiy Author: Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of Moscow Health Care Department Mr. Dr. Pavel Borisovich Gelezhe Author: Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of Moscow Health Care Department Mrs. Dr....

Bray F., Ferlay J., Soerjomataram I., Siegel R. L., Torre L. A., Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries // CA Cancer J. Clin. ‒ 2018. ‒ Vol. 68, № 6. ‒ Р. 394-424. doi: 10.3322/caac.21492. Morgan L., Choi H., Reid M. et al. Frequency of incidental findings and subsequent evaluation in low-dose computed tomographic scans for lung cancer screening. Ann. Am. Thorac. Soc., 2017, vol. 14, pp. 1450-1456. Alpert J. B., Naidich...