Keywords:
Cardiac, MR, Comparative studies, Inflammation, Retrospective, Case-control study, Not applicable
Authors:
R. palumbo1, D. De Stefano2, V. Cirimele2, A. tamburrano3, M. Luzietti4, V. BUFFA3, B. Beomonte Zobel2; 1roma, italia/IT, 2Rome/IT, 3roma/IT, 4Roma (RM)/IT
DOI:
10.26044/ecr2020/C-11556
Methods and materials
67 Cardiac Magnetic Resonance Imaging (CMR) was retrospectively evaluated of Patients with Hypertrophic Cardiomyopathy undergoing treatment at the U.O.C. of Cardiology (Cardiomyopathy Clinic) of the "San Camillo Forlanini" Hospital in Rome, carried out in the period from January 2017 to October 2018 at the U.O. Cardiovascular Radiology (Cardioscience Department) of the A.O.: "San Camillo Forlanini" in Rome. The Cardiac Magnetic Resonance Imaging (CMR) were performed with 1.5 T Magnet (Siemens Magnetom Avanto), using the following study protocol:
• Cine - SSFP cardiac axes (2 chambers, 4 chambers, 3 chambers, LVOT, short axis): (slice thickness: 8mm; TR 43.5ms; TE 2.18ms; FA 66 °; NEX 1; 25 segments).
• T2-STIR short axis (slice thickness: 9mm; TR 1108.75ms; TE 81ms; FA 180 °; NEX 1; matrix 256 x 163 FOV 256 x 212).
• MDC: gadoteric acid, 0.2mmol / Kg.
• Short axis perfusion: (slice thickness: 10 mm; gap 22 mm; TR 167.85 ms; TE 0.88 ms; FA 66 °; NEX 1).
• Delayed enhancement: Phase - Sensitive Inversion Recovery (PSIR) at 10 'from the administration of contrast medium. TI variable (about 320ms).
The presence / absence of myocardial edema (indicated by the pathological hyperintensity in T2 STIR sequences), the presence and extent of LGE and left ventricular function (the ventricular analysis was carried out using Syngovia software) were assessed.
The risk of sudden cardiac death was assessed in each patient by calculating the HCM Risk Score and the number of episodes of Unsupported Ventricular Tachycardia (TVNS) recorded in the 24h ECG.
For the statistical evaluation, the t-test and linear regression were used.