Purpose
Lung cancers associated with cystic airspaces are now increasingly recognized as a separate entity. The current understanding of this entity is limited, and these are being increasingly identified as a cause of delayed diagnosis. The incidence of pericystic lung cancers is unknown however; with many of the general public participating in lung cancer screening programs, the prevalence of pericystic lung cancers is becoming more apparent. Different morphological subtypes of this cancer exist, and a small number of cases have been reported in a few studies...
Methods and materials
Setting –District General hospital
Study design: Retrospective review
CT scans of patients with lung cancers discussed during the lung oncology MDT from 2017-19 were reviewed by two Consultant Thoracic Radiologists independently.
Results
37 patients with pericystic lung cancers and suspicious cystic airspaces were identified from 2017-19. There were 22 females and 15 males with an average age of 72 years. The total number of pericystic nodules, cancers and suspicious cystic airspaces was 44. Here is our analysis of these 44 lesions:
The averagesize of cysticairspace on the baseline scan was 21.7mm.
The number of lesions with a pericystic nodule on the baseline scan was 21. The average size of the pericystic nodule on the baseline scan was...
Conclusion
The pericystic lung cancers are becoming more prevalent and these are often misinterpreted. It is challenging to interpret pericystic changes or identify suspicious cystic airspaces in patients who have diffuse diseases like emphysema or fibrosis—as opposed to an isolated pericystic lesion in the otherwise normal lung parenchyma.
As there are no consensus guidelines for follow up of the precursor cystic airspaces or the management of pericystic nodules, these can prove to be a further diagnostic challenge.
Prospective studies are needed to assess changes in prognostic...
Personal information and conflict of interest
A. Vohra; Airdrie/UK - nothing to disclose L. Smart; Airdrie/UK - nothing to disclose P. R. Garnett; Airdrie/UK - nothing to disclose S. Baird; Airdrie/UK - nothing to disclose
References
1. Sheard, S., Moser, J., Sayer, C., Stefanidis, K., Devaraj, A. and Vlahos, I., 2018. Lung cancers associated with cystic airspaces: underrecognized features of early disease.RadioGraphics,38(3), pp.704-717.