Learning objectives
Provide a background for the dissemination of prostate cancer metastases.
Illustrate a case series of atypical presentations of metastatic prostate cancer in our institution.
Background
Background
Prostate malignancy is the most common non-cutaneous cancer in men, being an important cause of mortality. In recent years better survival have been reported thanks to screening tests such as the specific prostate antigen and development of better treatment for advanced disease. This has also led to a major quantity of imaging studies in these patients, with more probability of finding atypical metastases. The presence of metastases is what most influences prognosis, which is why the radiologist needs to be able to suspect them....
Findings and procedure details
Intracranial metastases
Paranasal sinuses (PNS) metastases:
Primary tumors are much more frequent in this location than metastases. Secondary involvement is more commonly associated with kidney, lung, chest, intestinal, adrenal, skin, thyroid gland, pancreas, and testis malignancy. In an autopsy series, PNS affectation occurred in 4.3% of metastatic patients. This may occur by hematogenous or lymphatic pathways. The most affected sinuses are the maxillary and sphenoidal PNS, unilaterally. It can be seen as a soft tissue invasive lesion, associated with osteoblastic bone lesions and erosions with...
Conclusion
Although bone is the most frequent metastatic site of prostate cancer, the radiologist must be aware of other potential sites of compromise, as their finding could change the patient’s prognosis significantly.
Personal information and conflict of interest
C. Leiva; Viña del Mar/CL - nothing to disclose P. Fuentes; Viña Del Mar, NOT APPLICABLE/CL - nothing to disclose J. Recasens; Viña del Mar/CL - nothing to disclose D. Villagran; Valparaíso/CL - nothing to disclose O. Chavez; Viña del Mar/CL - nothing to disclose
References
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Ng SJK, Sinha AK, Loi HY, Khor LK. Asymptomatic metastasis to cricoid from prostate carcinoma: an incidental finding detected on 18F-choline PET/CT. Jpn J Radiol. 2015 May;33(5):298–301.
Soma S. Penile Metastases From Prostate Adenocarcinoma: A Rare Presentation. J Clin Diagn Res. 2015
Akdemir F, Aldemir M, Çakar H, Güler G. Metastasis of prostate adenocarcinoma to the...