Keywords:
Performed at one institution, Observational, Retrospective, Ischaemia / Infarction, Diagnostic procedure, MR, Echocardiography, Cardiac
Authors:
E. Chiodi1, A. Cossu2, F. Pellegrino1, L. Marchetti1, A. Squerzanti1, A. Carnevale1, M. Giganti1, G. Benea3; 1Ferrara/IT, 2Ferrara, Fe/IT, 3Lagosanto (FE)/IT
DOI:
10.26044/ecr2020/C-14478
Methods and materials
From Cardiology Unit database we enrolled all patients with a diagnosis of STEMI on the basis of clinical presentation, electrocardiographic findings, and troponin elevation who underwent myocardial revascularization within 90 min from the onset of symptoms with the effective coronary flow after the procedure (TIMI III). Study inclusion criteria were an echocardiography exam performed with a dedicated protocol for speckle-tracking analysis within 7 days from the acute event and a CMR performed within 7 days and after 6 months for the study of LVR. Three echocardiographic parameters including LV ejection fraction (EF), GLS and SAS area by 2D-STE and 3 CMR indices including LV global function index (LV-GFI), myocardial salvage index (MSI), and MVO were calculated. LVR was defined as an increase in CMR LV end-diastolic volume (EDV) >15% after 6 months. The basal and 6-month values of the CMR parameters were compared as well as the values of the subgroups of patients with and without LVR. The following variables were included in the predictive analysis by evaluating the association between all the variables and LVR with univariable analysis subsequently followed by stepwise multivariable regression analysis.