Learning objectives
The purpose of this poster is to describe the frequency, associated risk factors, clinical complexities, and diagnostic challenges of multiple primary malignancies.
Background
With the advancement in diagnostic techniques, including more sophisticated imaging and genetic testing, doctors are now able to detect cancer more accurately and at earlier stages. Coupled with enhanced surveillance programs that monitor patients more closely for signs of cancer, these developments have significantly improved the early detection rates of multiple primary malignancies. Additionally, because cancer treatments have become more effective, patients are living longer, which increases the likelihood of developing another primary cancer over their lifetime. Consequently, the incidence of multiple primary malignancies is...
Findings and procedure details
Multiple primary tumors, according to the definition by IARC are primary malignant tumors of different histological origins in the same person. They can be divided into synchronous and metachronous based on the time interval of their occurrence. Synchronous primary tumors are diagnosed in the interval of 6 months and metachronous tumors arise in a period of more than 6 months. [Fig 1]The risk factors for developing multiple primary tumors can be classified into three main categories: host-related, lifestyle, and environmental factors. [4]Host-related factors, including genetic...
Conclusion
Understanding the risk of developing a second primary tumor in oncology patients and employing targeted diagnostic techniques can facilitate earlier detection. This approach enhances treatment effectiveness and significantly improves the patient's survival chances by allowing for timely intervention.
Personal information and conflict of interest
S. Hadjieva:
Nothing to disclose
K. P. Chupetlovska:
Nothing to disclose
P. G. Getsov:
Nothing to disclose
References
Bajdik CD, Abanto ZU, Spinelli JJ, et al. Identifying related cancer types based on their incidence among people with multiple cancers. Emerg Themes Epidemiol 2006;3:17.
Gaskin HS, Hardy RE, Fletcher RL. Multiple primary malignancies in black patients. J Natl Med Assoc 1981;73:1065–8. 15. Donin N, Filson C, Drakaki A, et al. Risk of second primary malignancies among cancer survivors in the United States, 1992 through 2008. Cancer 2016;122:3075–86.
Ferlay J, Steliarova-Foucher E, Lortet-Tieulent J, et al. Cancer incidence and mortality patterns in Europe: estimates for...