Type:
Poster Presentation
Keywords:
Cardiac, MR, CT, Echocardiography, Diagnostic procedure, Hyperplasia / Hypertrophy, Education and training, Image verification
Authors:
E. Pershina, O. Larina, E. A. Mershina, V. Sinitsyn; Moscow/RU
Methods and Materials
21 patients (m/f-11/10,
age 17-62 yrs,
mean age - 35.8±15,9 yrs) were diagnosed with HCM in our department in 2012: 8 – asymmetric septal hypertrophy (ASH) with sigmoid septal contour and outflow tract obstruction,
6 patients - ASH with reversed septal contour without outflow tract obstruction,
4 - apical form,
2 – midventricular form and 1 - focal HCM.
CMR protocol was performed at 1.5T scanner (Magnetom Avanto, Siemens AG) using multichannel surface coil with cardiac synchronization.
Breath-hold cine images were acquired with fast imaging using steady-state precession technique (TrueFISP).
Late gadolinium enhanced (LGE) images were obtained 10-15 minutes after intravenous injection of contrast medium.
Segmented inversion-recovery breath-hold T1-sequence was used.
Time of inversion was adjusted for each patient between 200 and 350 (more often 280-300) to achieve the optimal suppression of normal myocardium.
Left ventricle was examined in vertical long,
horizontal long and short axis positions.
The location,
extent and enhancement pattern of hyperenhanced myocardium were analyzed in a 17-segment AHA model.
Cine MR-images were quantitatively evaluated using Siemens cardiac image analysis software (ARGUS).
Echocardiogram was made in 3 cases when structural abnormalities were detected with CMR to quantify mid-ventricular and subaortic gradient of obstruction.
MDCT coronary angiography was performed at 64-slice scanner (Discovery CT750 HD,
GE) in 2 pts with ischemical patterns of LGE to exclude coronary stenoses.
Chest CT was performed in cases with LGE in non-hypertrophied segment to exclude systemic sarcoidosis.